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forked from KunnyKou's block: Rectangles for Chromosomes
forked from asminja's block: Rectangles for Chromosomes
forked from asminja's block: Rectangles for Chromosomes 2
xxxxxxxxxx<head> <meta charset="utf-8"> <script src="https://d3js.org/d3.v4.min.js"></script> <style> body { margin:0;position:fixed;top:0;right:0;bottom:0;left:0; } </style></head><body><script> var svg = d3.select("body").append("svg") .attr("width", 7000) .attr("height", 5000); d3.json("scratch_1.json", function(err, data) { var linedata = [{"Chromosome":"1","Gene_symbol":"ASTN1","Gene_Name":"Astrotactin ","Gene_Function":"neuronal adhesion molecule required for glial-guided migration of young postmitotic neuroblasts in cortical regions of developing brain","Spacing":"147","Interval_length":"147"},{"Chromosome":"1","Gene_symbol":"CAMTA1","Gene_Name":"Calmodulin binding transcription activator 1","Gene_Function":"transcription activator in a reporter expression system","Spacing":"356","Interval_length":"184"},{"Chromosome":"1","Gene_symbol":"CHD5","Gene_Name":"Chromodomain helicase DNA binding protein 5","Gene_Function":"protein that binds DNA through histones and regulates gene transcription","Spacing":"576","Interval_length":"195"},{"Chromosome":"1","Gene_symbol":"CHRM3","Gene_Name":"Cholinergic receptor muscarinic 3","Gene_Function":"mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.","Spacing":"729","Interval_length":"128"},{"Chromosome":"1","Gene_symbol":"CNST","Gene_Name":"Consortin","Gene_Function":"connexin sorting protein","Spacing":"864","Interval_length":"110"},{"Chromosome":"1","Gene_symbol":"FGGY","Gene_Name":"FGGY Carbohydrate Kinase Domain Containing","Gene_Function":"encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol","Spacing":"1000","Interval_length":"111"},{"Chromosome":"1","Gene_symbol":"HFM1","Gene_Name":"Hydroxymethylfurfural 1","Gene_Function":"ATP-dependent DNA helicase","Spacing":"1441","Interval_length":"416"},{"Chromosome":"1","Gene_symbol":"HIVEP3","Gene_Name":"Human Immunodeficiency Virus Type I Enhancer Binding Protein 3","Gene_Function":"gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family","Spacing":"1623","Interval_length":"157"},{"Chromosome":"1","Gene_symbol":"HS2ST1","Gene_Name":"Heparan sulfate 2-O-sulfotransferase 1","Gene_Function":"catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS)","Spacing":"1753","Interval_length":"105"},{"Chromosome":"1","Gene_symbol":"KIAA1026","Gene_Name":"Kazrin isoform A 1026","Gene_Function":"plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation","Spacing":"1943","Interval_length":"165"},{"Chromosome":"1","Gene_symbol":"LGTN","Gene_Name":"Ligatin","Gene_Function":"peripheral membrane protein found in mammalian and avian tissues during embryonic development and in early differentiated states","Spacing":"2112","Interval_length":"144"},{"Chromosome":"1","Gene_symbol":"LOC100130331","Gene_Name":"Locus 100130331","Gene_Function":"POTE ankyrin domain family, member F pseudogene","Spacing":"2263","Interval_length":"126"},{"Chromosome":"1","Gene_symbol":"PRDM16","Gene_Name":"PR domain zinc finger protein 16","Gene_Function":"transcription coregulator that controls the development of brown adipocytes in brown adipose tissue","Spacing":"2412","Interval_length":"124"},{"Chromosome":"1","Gene_symbol":"SLC30A10","Gene_Name":"Solute Carrier Family 30 Member 10","Gene_Function":"provides instructions for making a protein that transports the element manganese across cell membranes","Spacing":"2540","Interval_length":"103"},{"Chromosome":"1","Gene_symbol":"TTC4","Gene_Name":"Tetratricopeptide Repeat Domain 4","Gene_Function":"encodes a protein that contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions and chaperone activity","Spacing":"2718","Interval_length":"153"},{"Chromosome":"1","Gene_symbol":"ZP4","Gene_Name":"Zona Pellucida Glycoprotein 4","Gene_Function":"an extracellular matrix that surrounds the oocyte and early embryo","Spacing":"2869","Interval_length":"126"},{"Chromosome":"2","Gene_symbol":"ARHGAP15","Gene_Name":"Rho GTPase-activating protein 15","Gene_Function":"GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state","Spacing":"198","Interval_length":"198"},{"Chromosome":"2","Gene_symbol":"COLEC11","Gene_Name":"Collectin Subfamily Member 11","Gene_Function":"encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains","Spacing":"407","Interval_length":"184"},{"Chromosome":"2","Gene_symbol":"EHBP1","Gene_Name":"EH domain binding protein 1","Gene_Function":"encodes an Eps15 homology domain binding protein, and may play a role in endocytic trafficking","Spacing":"609","Interval_length":"177"},{"Chromosome":"2","Gene_symbol":"GREB1","Gene_Name":"Growth Regulation By Estrogen In Breast Cancer 1","Gene_Function":"estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway","Spacing":"799","Interval_length":"165"},{"Chromosome":"2","Gene_symbol":"IL1R2","Gene_Name":"Interleukin 1 Receptor Type 2","Gene_Function":"protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands","Spacing":"1146","Interval_length":"322"},{"Chromosome":"2","Gene_symbol":"INPP1","Gene_Name":"Inositol Polyphosphate-1-Phosphatase","Gene_Function":"involved in phosphatidylinositol signaling pathways","Spacing":"1335","Interval_length":"164"},{"Chromosome":"2","Gene_symbol":"KLHL29","Gene_Name":"Kelch Like Family Member 29","Gene_Function":"protein ubiquitination involved in ubiquitin-dependent protein catabolic process","Spacing":"1474","Interval_length":"114"},{"Chromosome":"2","Gene_symbol":"MAL","Gene_Name":"Myelin and lymphocyte protein","Gene_Function":"hydrophobic integral membrane protein belonging to the MAL family of proteolipids","Spacing":"1609","Interval_length":"110"},{"Chromosome":"2","Gene_symbol":"MAP4K4","Gene_Name":"Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4","Gene_Function":"kinase has been shown to specifically activate MAPK8/JNK","Spacing":"1757","Interval_length":"123"},{"Chromosome":"2","Gene_symbol":"MGAT5","Gene_Name":"Mannosyl (Alpha-1,6-)-Glycoprotein Beta-1,6-N-Acetyl-Glucosaminyltransferase","Gene_Function":"catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins","Spacing":"1931","Interval_length":"149"},{"Chromosome":"2","Gene_symbol":"MOGAT1","Gene_Name":"Monoacylglycerol O-Acyltransferase 1","Gene_Function":"catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids","Spacing":"2079","Interval_length":"123"},{"Chromosome":"2","Gene_symbol":"MYT1L","Gene_Name":"Myelin Transcription Factor 1 Like","Gene_Function":"belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system","Spacing":"2253","Interval_length":"149"},{"Chromosome":"2","Gene_symbol":"PSMD1","Gene_Name":"Proteasome 26S Subunit, Non-ATPase 1","Gene_Function":"one of the 19 essential subunits that contributes to the complete assembly of 19S proteasome complex","Spacing":"2439","Interval_length":"161"},{"Chromosome":"2","Gene_symbol":"PXDN","Gene_Name":"Peroxidasin","Gene_Function":"heme-containing peroxidase that is secreted into the extracellular matrix","Spacing":"2631","Interval_length":"167"},{"Chromosome":"2","Gene_symbol":"RAPGEF4","Gene_Name":"Rap Guanine Nucleotide Exchange Factor 4","Gene_Function":"encodes Epac2, functions as a guanine nucleotide exchange factor for the Ras-like small GTPase Rap upon cAMP stimulation","Spacing":"2773","Interval_length":"117"},{"Chromosome":"2","Gene_symbol":"RAPH1","Gene_Name":"Ras Association (RalGDS/AF-6) And Pleckstrin Homology Domains 1","Gene_Function":"belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration.","Spacing":"2914","Interval_length":"116"},{"Chromosome":"2","Gene_symbol":"SNTG2","Gene_Name":"Syntrophin Gamma 2","Gene_Function":"cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins","Spacing":"3039","Interval_length":"100"},{"Chromosome":"2","Gene_symbol":"SPAG16","Gene_Name":"Sperm Associated Antigen 16","Gene_Function":"encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells","Spacing":"3234","Interval_length":"170"},{"Chromosome":"2","Gene_symbol":"THNSL2","Gene_Name":"Threonine Synthase Like 2","Gene_Function":"catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia","Spacing":"3447","Interval_length":"188"},{"Chromosome":"2","Gene_symbol":"TMEFF2","Gene_Name":"Transmembrane Protein With EGF Like And Two Follistatin Like Domains 2","Gene_Function":"an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion","Spacing":"3636","Interval_length":"164"},{"Chromosome":"2","Gene_symbol":"VPS24","Gene_Name":"Vacuolar protein-sorting-associated protein 24","Gene_Function":"implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles","Spacing":"3793","Interval_length":"132"},{"Chromosome":"2","Gene_symbol":"VWA3B","Gene_Name":"Von Willebrand Factor A Domain Containing 3B","Gene_Function":"function in transcription, DNA repair, and ribosomal and membrane transport, as well as with the proteasome","Spacing":"3998","Interval_length":"180"},{"Chromosome":"2","Gene_symbol":"WIPF1","Gene_Name":"WAS/WASL Interacting Protein Family Member 1","Gene_Function":"plays an important role in the organization of the actin cytoskeleton","Spacing":"4159","Interval_length":"136"},{"Chromosome":"3","Gene_symbol":"ATXN7","Gene_Name":"Ataxin 7","Gene_Function":"acts as component of the STAGA transcription coactivator-HAT complex, mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation, and is necessary for microtubule cytoskeleton stabilization","Spacing":"104","Interval_length":"104"},{"Chromosome":"3","Gene_symbol":"C3orf67","Gene_Name":"Chromosome 3 Open Reading Frame 67","Gene_Function":"uncharacterized protein","Spacing":"232","Interval_length":"103"},{"Chromosome":"3","Gene_symbol":"CADM2","Gene_Name":"Cell Adhesion Molecule 2","Gene_Function":"encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily","Spacing":"363","Interval_length":"106"},{"Chromosome":"3","Gene_symbol":"CAV3","Gene_Name":"Caveolin-3","Gene_Function":"functions as a component of the caveolae plasma membranes found in most cell types","Spacing":"488","Interval_length":"100"},{"Chromosome":"3","Gene_symbol":"DLEC1","Gene_Name":"Deleted In Lung And Esophageal Cancer 1","Gene_Function":"acts as a tumor suppressor by inhibiting cell proliferation","Spacing":"815","Interval_length":"302"},{"Chromosome":"3","Gene_symbol":"EPHA6","Gene_Name":"Ephrin Receptor A6","Gene_Function":"receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells","Spacing":"1018","Interval_length":"178"},{"Chromosome":"3","Gene_symbol":"FAM157A","Gene_Name":"Family With Sequence Similarity 157 Member A","Gene_Function":"uncharacterized protein","Spacing":"1311","Interval_length":"268"},{"Chromosome":"3","Gene_symbol":"FBLN2","Gene_Name":"Fibulin 2","Gene_Function":"encodes an extracellular matrix protein, which belongs to the fibulin family","Spacing":"1470","Interval_length":"134"},{"Chromosome":"3","Gene_symbol":"FGF12","Gene_Name":"Fibroblast Growth Factor 12","Gene_Function":"possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion","Spacing":"1600","Interval_length":"105"},{"Chromosome":"3","Gene_symbol":"MAPKAPK3","Gene_Name":"Mitogen-Activated Protein Kinase-Activated Protein Kinase 3","Gene_Function":"encodes a member of the Ser/Thr protein kinase family, functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase","Spacing":"1728","Interval_length":"103"},{"Chromosome":"3","Gene_symbol":"PTPRG","Gene_Name":"Protein Tyrosine Phosphatase","Gene_Function":"signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation","Spacing":"1867","Interval_length":"114"},{"Chromosome":"3","Gene_symbol":"RBM6","Gene_Name":"RNA Binding Motif Protein 6","Gene_Function":"specifically binds poly(G) RNA homopolymers in vitro","Spacing":"1995","Interval_length":"103"},{"Chromosome":"3","Gene_symbol":"RBMS3","Gene_Name":"RNA Binding Motif Single Stranded Interacting Protein 3","Gene_Function":"encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family, binds poly(A) and poly(U) oligoribonucleotides","Spacing":"2181","Interval_length":"161"},{"Chromosome":"3","Gene_symbol":"ROBO2","Gene_Name":"Roundabout Guidance Receptor 2","Gene_Function":"transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration","Spacing":"2336","Interval_length":"130"},{"Chromosome":"3","Gene_symbol":"SLCO2A1","Gene_Name":"Solute Carrier Organic Anion Transporter Family Member 2A1","Gene_Function":"mediates the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation, transports PGD2, as well as PGE1, PGE2 and PGF2A","Spacing":"2461","Interval_length":"100"},{"Chromosome":"3","Gene_symbol":"ZBTB20","Gene_Name":"Zinc Finger And BTB Domain Containing 20","Gene_Function":"transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses","Spacing":"2611","Interval_length":"125"},{"Chromosome":"4","Gene_symbol":"ANXA10","Gene_Name":"Annexin A10","Gene_Function":"calcium-dependent phospholipid-binding protein family that plays a role in the regulation of cellular growth and in signal transduction pathways","Spacing":"196","Interval_length":"196"},{"Chromosome":"4","Gene_symbol":"ARHGAP10","Gene_Name":"Rho GTPase Activating Protein 10","Gene_Function":"regulation of activated PAK-2p34 by proteasome mediated degradation and bacterial invasion of epithelial cells","Spacing":"368","Interval_length":"147"},{"Chromosome":"4","Gene_symbol":"COL25A1","Gene_Name":"Collagen Type 25 Alpha 1 Chain","Gene_Function":"encodes a brain-specific membrane associated collagen","Spacing":"524","Interval_length":"131"},{"Chromosome":"4","Gene_symbol":"CPLX1","Gene_Name":"Complexin 1","Gene_Function":"cytosolic proteins that function in synaptic vesicle exocytosis","Spacing":"699","Interval_length":"150"},{"Chromosome":"4","Gene_symbol":"INPP4B","Gene_Name":"Inositol polyphosphate 4-phosphatase type II","Gene_Function":"dual specificity phosphatase, involved in phosphatidylinositol signaling pathways","Spacing":"846","Interval_length":"122"},{"Chromosome":"4","Gene_symbol":"NUP54","Gene_Name":"Nucleoporin 54","Gene_Function":"component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane","Spacing":"1048","Interval_length":"177"},{"Chromosome":"4","Gene_symbol":"POLN","Gene_Name":"DNA Polymerase Nu","Gene_Function":"encodes a DNA polymerase type-A family member, plays a role in DNA repair and homologous recombination","Spacing":"1174","Interval_length":"101"},{"Chromosome":"4","Gene_symbol":"PROM1","Gene_Name":"Prominin 1","Gene_Function":"encodes a pentaspan transmembrane glycoprotein, localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation","Spacing":"1299","Interval_length":"100"},{"Chromosome":"4","Gene_symbol":"SORCS2","Gene_Name":"Sortilin Related VPS10 Domain Containing Receptor 2","Gene_Function":"encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins, strongly expressed in the central nervous system","Spacing":"1426","Interval_length":"102"},{"Chromosome":"4","Gene_symbol":"TMEM154","Gene_Name":"Transmembrane Protein 154","Gene_Function":"integral component of membrane","Spacing":"1552","Interval_length":"101"},{"Chromosome":"4","Gene_symbol":"ZNF509","Gene_Name":"Zinc finger protein 509","Gene_Function":"potent transcriptional activator of CDKN1A","Spacing":"1732","Interval_length":"155"},{"Chromosome":"5","Gene_symbol":"BTNL9","Gene_Name":"Butyrophilin Like 9","Gene_Function":"functions in immune system and class I MHC mediated antigen processing and presentation","Spacing":"169","Interval_length":"169"},{"Chromosome":"5","Gene_symbol":"CTNNA1","Gene_Name":"Catenin Alpha 1","Gene_Function":"encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell","Spacing":"307","Interval_length":"113"},{"Chromosome":"5","Gene_symbol":"CTNND2","Gene_Name":"Catenin Delta 2","Gene_Function":"encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation","Spacing":"504","Interval_length":"172"},{"Chromosome":"5","Gene_symbol":"DEPDC1B","Gene_Name":"DEP Domain Containing 1B","Gene_Function":"signaling by GPCR and p75 NTR receptor-mediated signalling","Spacing":"629","Interval_length":"100"},{"Chromosome":"5","Gene_symbol":"FSTL4","Gene_Name":"Follistatin Like 4","Gene_Function":"primary function is the binding and bioneutralization of members of the TGF-? superfamily","Spacing":"754","Interval_length":"100"},{"Chromosome":"5","Gene_symbol":"GPR98","Gene_Name":"G protein-coupled receptor 98","Gene_Function":"transmembrane protein that mediates cellular signaling","Spacing":"905","Interval_length":"126"},{"Chromosome":"5","Gene_symbol":"KCNIP1","Gene_Name":"Potassium Voltage-Gated Channel Interacting Protein 1","Gene_Function":"protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium","Spacing":"1039","Interval_length":"109"},{"Chromosome":"5","Gene_symbol":"RAD50","Gene_Name":"Double Strand Break Repair Protein","Gene_Function":"involved in DNA double-strand break repair","Spacing":"1193","Interval_length":"129"},{"Chromosome":"5","Gene_symbol":"SGCD","Gene_Name":"Sarcoglycan delta","Gene_Function":"protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC)","Spacing":"1380","Interval_length":"162"},{"Chromosome":"5","Gene_symbol":"SNCAIP","Gene_Name":"Synuclein Alpha Interacting Protein","Gene_Function":"encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration","Spacing":"1522","Interval_length":"117"},{"Chromosome":"5","Gene_symbol":"STK32A","Gene_Name":"Serine/Threonine Kinase 32A","Gene_Function":"involves transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity","Spacing":"1745","Interval_length":"198"},{"Chromosome":"5","Gene_symbol":"SV2C","Gene_Name":"Synaptic Vesicle Glycoprotein 2C","Gene_Function":"plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission, positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles ","Spacing":"1935","Interval_length":"165"},{"Chromosome":"5","Gene_symbol":"TRIO","Gene_Name":"Trio Rho Guanine Nucleotide Exchange Factor","Gene_Function":"encodes a large protein that functions as a GDP to GTP exchange factor, promotes the reorganization of the actin cytoskeleton (thereby playing a role in cell migration and growth)","Spacing":"2104","Interval_length":"144"},{"Chromosome":"5","Gene_symbol":"UIMC1","Gene_Name":"Ubiquitin Interaction Motif Containing 1","Gene_Function":"encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions, binds ubiquitinated lysine 63 of histone H2A and H2AX, and may also function as a repressor of transcription","Spacing":"2234","Interval_length":"105"},{"Chromosome":"5","Gene_symbol":"WWC1","Gene_Name":"WW and C2 Domain Containing 1","Gene_Function":"protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1, alleles of this gene have been found that enhance memory in some individuals","Spacing":"2361","Interval_length":"102"},{"Chromosome":"6","Gene_symbol":"DNAH8","Gene_Name":"Dynein Axonemal Heavy Chain 8","Gene_Function":"protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility, axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules","Spacing":"132","Interval_length":"132"},{"Chromosome":"6","Gene_symbol":"ELOVL2","Gene_Name":"Elongation Of Very Long Chain Fatty Acids Elongase 2","Gene_Function":"catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle","Spacing":"257","Interval_length":"100"},{"Chromosome":"6","Gene_symbol":"ESR1","Gene_Name":"Estrogen Receptor 1","Gene_Function":"encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription","Spacing":"424","Interval_length":"142"},{"Chromosome":"6","Gene_symbol":"HIST1H2BL","Gene_Name":"Histone Cluster 1 H2B Family Member L","Gene_Function":"basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes","Spacing":"565","Interval_length":"116"},{"Chromosome":"6","Gene_symbol":"JARID2","Gene_Name":"Jumonji And AT-Rich Interaction Domain Containing 2","Gene_Function":"encoded protein is a DNA-binding protein that functions as a transcriptional repressor, regulator of histone methyltransferase complexes that play an essential role in embryonic development ","Spacing":"745","Interval_length":"155"},{"Chromosome":"6","Gene_symbol":"LY86","Gene_Name":"Lymphocyte Antigen 86","Gene_Function":"may cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production, important for efficient CD180 cell surface expression","Spacing":"920","Interval_length":"150"},{"Chromosome":"6","Gene_symbol":"SRPK1","Gene_Name":"Serine/Arginine-Rich Splicing Factor Kinase 1","Gene_Function":"encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors","Spacing":"1114","Interval_length":"169"},{"Chromosome":"6","Gene_symbol":"UBR2","Gene_Name":"Ubiquitin Protein Ligase E3 Component N-Recognin 2","Gene_Function":"encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation","Spacing":"1335","Interval_length":"196"},{"Chromosome":"6","Gene_symbol":"UTRN","Gene_Name":"Utrophin","Gene_Function":"protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering","Spacing":"1495","Interval_length":"135"},{"Chromosome":"7","Gene_symbol":"AMPH","Gene_Name":"Amphiphysin","Gene_Function":"encodes a protein associated with the cytoplasmic surface of synaptic vesicles","Spacing":"116","Interval_length":"116"},{"Chromosome":"7","Gene_symbol":"C7orf23","Gene_Name":"Chromosome 7 Open Reading Frame 23","Gene_Function":"uncharacterized protein","Spacing":"241","Interval_length":"100"},{"Chromosome":"7","Gene_symbol":"CADPS2","Gene_Name":"Calcium Dependent Secretion Activator 2","Gene_Function":"encodes a member of the calcium-dependent activator of secretion (CAPS) protein family, which are calcium binding proteins that regulate the exocytosis of synaptic and dense-core vesicles in neurons and neuroendocrine cells","Spacing":"373","Interval_length":"107"},{"Chromosome":"7","Gene_symbol":"CALN1","Gene_Name":"Calneuron 1","Gene_Function":"encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family, encoded protein contains two EF-hand domains and potential calcium-binding sites","Spacing":"541","Interval_length":"143"},{"Chromosome":"7","Gene_symbol":"CUX1","Gene_Name":"Cut Like Homeobox 1","Gene_Function":"protein encoded by this gene is a member of the homeodomain family of DNA binding proteins, may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession","Spacing":"683","Interval_length":"117"},{"Chromosome":"7","Gene_symbol":"DPP6","Gene_Name":"Dipeptidyl Peptidase Like 6","Gene_Function":"encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases","Spacing":"828","Interval_length":"120"},{"Chromosome":"7","Gene_symbol":"FLJ40852","Gene_Name":"Uncharacterized full length 40852","Gene_Function":"RNA Gene, and is affiliated with the ncRNA class","Spacing":"1035","Interval_length":"182"},{"Chromosome":"7","Gene_symbol":"KPNA7","Gene_Name":"Karyopherin Subunit Alpha 7","Gene_Function":"functions in nuclear protein import","Spacing":"1210","Interval_length":"150"},{"Chromosome":"7","Gene_symbol":"MAGI2","Gene_Name":"Membrane Associated Guanylate Kinase","Gene_Function":"acts as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins","Spacing":"1374","Interval_length":"139"},{"Chromosome":"7","Gene_symbol":"MLXIPL","Gene_Name":"MLX Interacting Protein Like","Gene_Function":"encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily","Spacing":"1602","Interval_length":"203"},{"Chromosome":"7","Gene_symbol":"MYH16","Gene_Name":"Myosin heavy chain 16","Gene_Function":"encodes a sarcomeric myosin heavy chain","Spacing":"1768","Interval_length":"141"},{"Chromosome":"7","Gene_symbol":"PLXNA4","Gene_Name":"Plexin A4","Gene_Function":"coreceptor for SEMA3A, necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton","Spacing":"1923","Interval_length":"130"},{"Chromosome":"7","Gene_symbol":"STYXL1","Gene_Name":"Serine/Threonine/Tyrosine Interacting Like 1","Gene_Function":"probable pseudophosphatase, contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase","Spacing":"2132","Interval_length":"184"},{"Chromosome":"7","Gene_symbol":"TMEM195","Gene_Name":"Transmembrane protein 195","Gene_Function":"participates in fatty acid biosynthetic process and oxidation reduction","Spacing":"2281","Interval_length":"124"},{"Chromosome":"7","Gene_symbol":"ZP3","Gene_Name":"Zona Pellucida Glycoprotein 3","Gene_Function":"an extracellular matrix that surrounds the oocyte and early embryo","Spacing":"2456","Interval_length":"150"},{"Chromosome":"8","Gene_symbol":"ADRA1A","Gene_Name":"Adrenoceptor Alpha 1A","Gene_Function":"activates mitogenic responses and regulate growth and proliferation of many cells","Spacing":"132","Interval_length":"132"},{"Chromosome":"8","Gene_symbol":"ANK1","Gene_Name":"Ankyrin 1","Gene_Function":"proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains","Spacing":"318","Interval_length":"161"},{"Chromosome":"8","Gene_symbol":"ARHGEF10","Gene_Name":"Rho Guanine Nucleotide Exchange Factor 10","Gene_Function":"Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis","Spacing":"509","Interval_length":"166"},{"Chromosome":"8","Gene_symbol":"ASAP1","Gene_Name":"ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 1","Gene_Function":"encodes an ADP-ribosylation factor (ARF) GTPase-activating protein","Spacing":"683","Interval_length":"149"},{"Chromosome":"8","Gene_symbol":"BAI1","Gene_Name":"Brain-specific angiogenesis inhibitor 1","Gene_Function":"phosphatidylserine receptor that enhances the engulfment of apoptotic cells","Spacing":"839","Interval_length":"131"},{"Chromosome":"8","Gene_symbol":"COL22A1","Gene_Name":"Collagen Type 22 Alpha 1 Chain","Gene_Function":"acts as a cell adhesion ligand for skin epithelial cells and fibroblasts","Spacing":"964","Interval_length":"100"},{"Chromosome":"8","Gene_symbol":"CPNE3","Gene_Name":"Copine 3","Gene_Function":"calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation","Spacing":"1102","Interval_length":"113"},{"Chromosome":"8","Gene_symbol":"CSMD1","Gene_Name":"CUB And Sushi Multiple Domains 1","Gene_Function":"potential suppressor of squamous cell carcinomas","Spacing":"1252","Interval_length":"125"},{"Chromosome":"8","Gene_symbol":"NCALD","Gene_Name":"Neurocalcin Delta","Gene_Function":"encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins","Spacing":"1437","Interval_length":"160"},{"Chromosome":"8","Gene_symbol":"PKHD1L1","Gene_Name":"Polycystic Kidney And Hepatic Disease 1","Gene_Function":"homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor withinducible T lymphocyte expression ","Spacing":"1625","Interval_length":"163"},{"Chromosome":"8","Gene_symbol":"PREX2","Gene_Name":"Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 2","Gene_Function":"protein encoded by this gene belongs to the phosphatidylinositol 3,4,5-trisphosphate (PIP3)-dependent Rac exchanger (PREX) family, which are Dbl-type guanine-nucleotide exchange factors for Rac family small G proteins","Spacing":"1825","Interval_length":"175"},{"Chromosome":"8","Gene_symbol":"RBPMS","Gene_Name":"RNA Binding Protein With Multiple Splicing","Gene_Function":"encodes a member of the RNA recognition motif family of RNA-binding proteins","Spacing":"1950","Interval_length":"100"},{"Chromosome":"8","Gene_symbol":"SGCZ","Gene_Name":"Sarcoglycan Zeta","Gene_Function":"component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix","Spacing":"2095","Interval_length":"120"},{"Chromosome":"8","Gene_symbol":"SLC39A14","Gene_Name":"Solute Carrier Family 39 Member 14","Gene_Function":"an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation","Spacing":"2238","Interval_length":"118"},{"Chromosome":"9","Gene_symbol":"ADAMTSL2","Gene_Name":"ADAMTS Like 2","Gene_Function":"encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family","Spacing":"256","Interval_length":"256"},{"Chromosome":"9","Gene_symbol":"ASTN2","Gene_Name":"Astrotactin 2","Gene_Function":"mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons","Spacing":"381","Interval_length":"100"},{"Chromosome":"9","Gene_symbol":"C9orf68","Gene_Name":"Chromosome 9 Open Reading Frame 68","Gene_Function":"uncharacterized protein","Spacing":"506","Interval_length":"100"},{"Chromosome":"9","Gene_symbol":"C9orf96","Gene_Name":"Chromosome 9 Open Reading Frame 96","Gene_Function":"uncharacterized protein","Spacing":"662","Interval_length":"131"},{"Chromosome":"9","Gene_symbol":"CNTNAP3","Gene_Name":"Contactin Associated Protein-Like 3","Gene_Function":"mediate neuron-glial interactions in vertebrates and glial-glial contact","Spacing":"789","Interval_length":"102"},{"Chromosome":"9","Gene_symbol":"DBH","Gene_Name":"Dopamine Beta-Hydroxylase","Gene_Function":"present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine","Spacing":"934","Interval_length":"120"},{"Chromosome":"9","Gene_symbol":"DENND1A","Gene_Name":"Connecdenn Domain Containing 1A","Gene_Function":"function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2","Spacing":"1175","Interval_length":"216"},{"Chromosome":"9","Gene_symbol":"EPB41L4B","Gene_Name":"Erythrocyte Membrane Protein Band 4.1 Like 4B","Gene_Function":"up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18, involved in the regulation of the circumferential actomyosin belt in epithelial cells, and promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing","Spacing":"1310","Interval_length":"110"},{"Chromosome":"9","Gene_symbol":"LINGO2","Gene_Name":"Leucine Rich Repeat And Ig Domain Containing 2","Gene_Function":"positive regulation of synapse assembly","Spacing":"1462","Interval_length":"127"},{"Chromosome":"9","Gene_symbol":"LMX1B","Gene_Name":"LIM Homeobox Transcription Factor 1 Beta","Gene_Function":"functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons","Spacing":"1609","Interval_length":"122"},{"Chromosome":"9","Gene_symbol":"NACC2","Gene_Name":"NACC Family Member 2","Gene_Function":"functions as a transcriptional repressor through its association with the NuRD complex","Spacing":"1810","Interval_length":"176"},{"Chromosome":"9","Gene_symbol":"PTPRD","Gene_Name":"Protein Tyrosine Phosphatase","Gene_Function":"signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation","Spacing":"1991","Interval_length":"156"},{"Chromosome":"10","Gene_symbol":"ADARB2","Gene_Name":"Adenosine Deaminase, RNA Specific B2 (Inactive)","Gene_Function":"encodes a member of the double-stranded RNA adenosine deaminase family of RNA-editing enzymes and may play a regulatory role in RNA editing","Spacing":"123","Interval_length":"123"},{"Chromosome":"10","Gene_symbol":"ADD3","Gene_Name":"Adducin 3","Gene_Function":"membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues","Spacing":"266","Interval_length":"118"},{"Chromosome":"10","Gene_symbol":"ANTXRL","Gene_Name":"Anthrax Toxin Receptor-Like","Gene_Function":"Protein Coding gene. GO annotations related to this gene include receptor activity. An important paralog of this gene is ANTXR1","Spacing":"392","Interval_length":"101"},{"Chromosome":"10","Gene_symbol":"JAKMIP3","Gene_Name":"Janus Kinase And Microtubule Interacting Protein 3","Gene_Function":"members of the golgin family of proteins and may be responsible for Golgi structure or function","Spacing":"601","Interval_length":"184"},{"Chromosome":"10","Gene_symbol":"OLAH","Gene_Name":"Oleoyl-ACP Hydrolase","Gene_Function":"In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex","Spacing":"743","Interval_length":"117"},{"Chromosome":"10","Gene_symbol":"PCDH15","Gene_Name":"Protocadherin Related 15","Gene_Function":"Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function.","Spacing":"868","Interval_length":"100"},{"Chromosome":"10","Gene_symbol":"SFMBT2","Gene_Name":"Scm-Like With Four Mbt Domains 2","Gene_Function":"Transcriptional repressor of HOXB13 gene.","Spacing":"1071","Interval_length":"178"},{"Chromosome":"10","Gene_symbol":"SORCS3","Gene_Name":"Sortilin Related VPS10 Domain Containing Receptor 3","Gene_Function":"encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family","Spacing":"1208","Interval_length":"112"},{"Chromosome":"11","Gene_symbol":"FAT3","Gene_Name":"FAT Atypical Cadherin 3","Gene_Function":"May play a role in the interactions between neurites derived from specific subsets of neurons during development.","Spacing":"209","Interval_length":"209"},{"Chromosome":"11","Gene_symbol":"FCHSD2","Gene_Name":"FCH And Double SH3 Domains 2","Gene_Function":"Expressed in Hair Cell Stereocilia and Cuticular Plate and Regulate Actin Polymerization","Spacing":"340","Interval_length":"106"},{"Chromosome":"11","Gene_symbol":"GRM5","Gene_Name":"Glutamate Metabotropic Receptor 5","Gene_Function":"G-protein coupled receptor for glutamate.","Spacing":"518","Interval_length":"153"},{"Chromosome":"11","Gene_symbol":"MICALCL","Gene_Name":"MICAL C-Terminal Like","Gene_Function":"cooperate with MAPK1/ERK2 via an intracellular signal transduction pathway in the morphogenetic development of round spermatids to spermatozoa.","Spacing":"695","Interval_length":"152"},{"Chromosome":"11","Gene_symbol":"NTM","Gene_Name":"Neurotrimin","Gene_Function":"Neural cell adhesion molecule.","Spacing":"940","Interval_length":"220"},{"Chromosome":"11","Gene_symbol":"PLAC1L","Gene_Name":"Placenta Specific 1","Gene_Function":"May play a role in placental development.","Spacing":"1135","Interval_length":"170"},{"Chromosome":"11","Gene_symbol":"PTPRJ","Gene_Name":"Protein Tyrosine Phosphatase, Receptor Type J","Gene_Function":"Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling","Spacing":"1261","Interval_length":"101"},{"Chromosome":"11","Gene_symbol":"SERGEF","Gene_Name":"Secretion Regulating Guanine Nucleotide Exchange Factor","Gene_Function":"Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.","Spacing":"1415","Interval_length":"129"},{"Chromosome":"11","Gene_symbol":"SWAP70","Gene_Name":"SWAP Switching B-Cell Complex Subunit 70","Gene_Function":" transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling","Spacing":"1566","Interval_length":"126"},{"Chromosome":"12","Gene_symbol":"ACACB","Gene_Name":"Acetyl-CoA Carboxylase Beta","Gene_Function":"Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-Co","Spacing":"141","Interval_length":"141"},{"Chromosome":"12","Gene_symbol":"ANAPC7","Gene_Name":"Anaphase Promoting Complex Subunit 7","Gene_Function":"This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C)","Spacing":"267","Interval_length":"101"},{"Chromosome":"12","Gene_symbol":"ANO2","Gene_Name":"Anoctamin 2","Gene_Function":"Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction","Spacing":"434","Interval_length":"142"},{"Chromosome":"12","Gene_symbol":"EFCAB4B","Gene_Name":"Calcium Release Activated Channel Regulator 2A","Gene_Function":"Ca(2+)-binding protein that plays a key role in store-operated Ca(2+) entry (SOCE) in T-cells by regulating CRAC channel activation.","Spacing":"613","Interval_length":"154"},{"Chromosome":"12","Gene_symbol":"ERC1","Gene_Name":"ELKS/RAB6-Interacting/CAST Family Member 1","Gene_Function":"Regulatory subunit of the IKK complex.","Spacing":"795","Interval_length":"157"},{"Chromosome":"12","Gene_symbol":"FRS2","Gene_Name":"Fibroblast Growth Factor Receptor Substrate 2","Gene_Function":"Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways","Spacing":"993","Interval_length":"173"},{"Chromosome":"12","Gene_symbol":"LASS5","Gene_Name":"Ceramide Synthase 5","Gene_Function":"Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity).","Spacing":"1129","Interval_length":"111"},{"Chromosome":"12","Gene_symbol":"SLC2A14","Gene_Name":"Solute Carrier Family 2 Member 14","Gene_Function":"Facilitative glucose transporter (By similarity). May have a specific function related to spermatogenesis.","Spacing":"1322","Interval_length":"168"},{"Chromosome":"12","Gene_symbol":"ST8SIA1","Gene_Name":"ST8 Alpha-N-Acetyl-Neuraminide Alpha-2,8-Sialyltransferase 1","Gene_Function":"Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid.","Spacing":"1474","Interval_length":"127"},{"Chromosome":"13","Gene_symbol":"C13orf15","Gene_Name":"Regulator Of Cell Cycle","Gene_Function":"Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.","Spacing":"102","Interval_length":"102"},{"Chromosome":"13","Gene_symbol":"DACH1","Gene_Name":"Dachshund Family Transcription Factor 1","Gene_Function":"Transcription factor that is involved in regulation of organogenesis","Spacing":"259","Interval_length":"132"},{"Chromosome":"13","Gene_symbol":"FNDC3A","Gene_Name":"Fibronectin Type III Domain Containing 3A","Gene_Function":"Mediates spermatid-Sertoli adhesion during spermatogenesis.","Spacing":"414","Interval_length":"130"},{"Chromosome":"13","Gene_symbol":"MCF2L","Gene_Name":"MCF.2 Cell Line Derived Transforming Sequence Like","Gene_Function":"Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity).","Spacing":"574","Interval_length":"135"},{"Chromosome":"13","Gene_symbol":"PCCA","Gene_Name":"Propionyl-CoA Carboxylase Alpha Subunit","Gene_Function":"The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]","Spacing":"1014","Interval_length":"415"},{"Chromosome":"13","Gene_symbol":"RASA3","Gene_Name":"RAS P21 Protein Activator 3","Gene_Function":"Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.","Spacing":"1221","Interval_length":"182"},{"Chromosome":"13","Gene_symbol":"TNFSF13B","Gene_Name":"Tumor Necrosis Factor Superfamily Member 13b","Gene_Function":"Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors.","Spacing":"1432","Interval_length":"186"},{"Chromosome":"13","Gene_symbol":"TUBGCP3","Gene_Name":"Tubulin Gamma Complex Associated Protein 3","Gene_Function":"Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.","Spacing":"1612","Interval_length":"155"},{"Chromosome":"14","Gene_symbol":"GPHN","Gene_Name":"Gephyrin","Gene_Function":"Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.","Spacing":"178","Interval_length":"178"},{"Chromosome":"14","Gene_symbol":"NRXN3","Gene_Name":"Neurexin 3","Gene_Function":"Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.","Spacing":"303","Interval_length":"100"},{"Chromosome":"15","Gene_symbol":"ANXA2","Gene_Name":"Annexin A2","Gene_Function":"Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 ","Spacing":"100","Interval_length":"100"},{"Chromosome":"15","Gene_symbol":"ASB7","Gene_Name":"Ankyrin Repeat And SOCS Box Containing 7","Gene_Function":"Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.","Spacing":"106","Interval_length":"106"},{"Chromosome":"15","Gene_symbol":"EFTUD1","Gene_Name":"Elongation Factor Like GTPase 1","Gene_Function":"Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.","Spacing":"249","Interval_length":"118"},{"Chromosome":"15","Gene_symbol":"NEDD4","Gene_Name":"Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase","Gene_Function":"This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN","Spacing":"392","Interval_length":"118"},{"Chromosome":"15","Gene_symbol":"POLG","Gene_Name":"DNA polymerase gamma, catalytic subunit","Gene_Function":"The POLG gene provides instructions for making the active piece, called the alpha subunit, of a protein called polymerase gamma (pol ?)","Spacing":"655","Interval_length":"238"},{"Chromosome":"15","Gene_symbol":"USP3","Gene_Name":"Ubiquitin Specific Peptidase 3","Gene_Function":"Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.","Spacing":"855","Interval_length":"175"},{"Chromosome":"16","Gene_symbol":"A2BP1","Gene_Name":"RNA Binding Protein, Fox-1 Homolog 1","Gene_Function":"RNA-binding protein that regulates alternative splicing events by binding to 5-UGCAUGU-3 elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.","Spacing":"150","Interval_length":"150"},{"Chromosome":"16","Gene_symbol":"AMFR","Gene_Name":"Autocrine Motility Factor Receptor","Gene_Function":"This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. [provided by RefSeq, Feb 2012]","Spacing":"302","Interval_length":"127"},{"Chromosome":"16","Gene_symbol":"C16orf62","Gene_Name":"Chromosome 16 Open Reading Frame 62","Gene_Function":"Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes. Seems not to be required for CCC complex stability (PubMed:25355947).","Spacing":"467","Interval_length":"140"},{"Chromosome":"16","Gene_symbol":"HS3ST4","Gene_Name":"Heparan Sulfate-Glucosamine 3-Sulfotransferase 4","Gene_Function":"Sulfotransferase that utilizes 3-phospho-5-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate (By similarity).","Spacing":"592","Interval_length":"100"},{"Chromosome":"16","Gene_symbol":"XYLT1","Gene_Name":"Xylosyltransferase 1","Gene_Function":"Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.","Spacing":"746","Interval_length":"129"},{"Chromosome":"16","Gene_symbol":"ZFHX3","Gene_Name":"Zinc Finger Homeobox 3","Gene_Function":"Transcriptional regulator which can act as an activator or a repressor","Spacing":"894","Interval_length":"123"},{"Chromosome":"17","Gene_symbol":"ACCN1","Gene_Name":"Acid Sensing Ion Channel Subunit 2","Gene_Function":"Acid-sensing ion channels (ASIC) are members of the ENaC/Deg (epithelial amiloride-sensitive Na+ channel and degenerin) family of ion channels and are widely expressed in neurons of the central and peripheral nervous system.","Spacing":"100","Interval_length":"100"},{"Chromosome":"17","Gene_symbol":"PITPNM3","Gene_Name":"PITPNM Family Member 3","Gene_Function":"Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.","Spacing":"289","Interval_length":"164"},{"Chromosome":"17","Gene_symbol":"TNFRSF13B","Gene_Name":"TNF Receptor Superfamily Member 13B","Gene_Function":"Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.","Spacing":"514","Interval_length":"200"},{"Chromosome":"17","Gene_symbol":"USP6","Gene_Name":"Ubiquitin Specific Peptidase 6","Gene_Function":"Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.","Spacing":"639","Interval_length":"100"},{"Chromosome":"18","Gene_symbol":"ARHGAP28","Gene_Name":"Rho GTPase Activating Protein 28","Gene_Function":"GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.","Spacing":"101","Interval_length":"101"},{"Chromosome":"18","Gene_symbol":"CCDC102B","Gene_Name":"Coiled-Coil Domain Containing 102B","Gene_Function":"CCDC102B (Coiled-Coil Domain Containing 102B) is a Protein Coding gene. An important paralog of this gene is CCDC102A.","Spacing":"253","Interval_length":"127"},{"Chromosome":"18","Gene_symbol":"GALR1","Gene_Name":"Galanin Receptor 1","Gene_Function":"Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.","Spacing":"420","Interval_length":"142"},{"Chromosome":"18","Gene_symbol":"HSBP1L1","Gene_Name":"Heat Shock Factor Binding Protein 1 Like 1","Gene_Function":"HSBP1L1 (Heat Shock Factor Binding Protein 1 Like 1) is a Protein Coding gene.","Spacing":"550","Interval_length":"105"},{"Chromosome":"18","Gene_symbol":"LAMA1","Gene_Name":"Laminin Subunit Alpha 1","Gene_Function":"Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.","Spacing":"683","Interval_length":"108"},{"Chromosome":"18","Gene_symbol":"OSBPL1A","Gene_Name":"Oxysterol Binding Protein Like 1A","Gene_Function":"Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193).","Spacing":"824","Interval_length":"116"},{"Chromosome":"18","Gene_symbol":"RIOK3","Gene_Name":"RIO Kinase 3","Gene_Function":"RIOK3 (RIO Kinase 3) is a Protein Coding gene. Among its related pathways are rRNA processing in the nucleus and cytosol and Gene Expression. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and phosphotransferase activity, alcohol group as acceptor. An important paralog of this gene is RIOK1.","Spacing":"959","Interval_length":"110"},{"Chromosome":"19","Gene_symbol":"C3","Gene_Name":"Complement C3","Gene_Function":"Plays a central role in the activation of complement system.","Spacing":"166","Interval_length":"166"},{"Chromosome":"19","Gene_symbol":"CREB3L3","Gene_Name":"CAMP Responsive Element Binding Protein 3 Like 3","Gene_Function":"binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression.","Spacing":"328","Interval_length":"137"},{"Chromosome":"19","Gene_symbol":"INSR","Gene_Name":"Insulin Receptor","Gene_Function":"Encodes ?preproprotein?that?is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor.","Spacing":"521","Interval_length":"168"},{"Chromosome":"19","Gene_symbol":"LPHN1","Gene_Name":"Latrophilin-1","Gene_Function":"Gene encodes a member of the latrophilin subfamily of G protein-coupled receptors?that?may function in both cell adhesion and signal transduction.","Spacing":"694","Interval_length":"148"},{"Chromosome":"19","Gene_symbol":"OSCAR","Gene_Name":"Osteoclast Associated, Immunoglobulin-Like Receptor","Gene_Function":"Plays critical roles in the regulation of both innate and adaptive immune responses","Spacing":"820","Interval_length":"101"},{"Chromosome":"19","Gene_symbol":"PIP5K1C","Gene_Name":"Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma","Gene_Function":"The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration.","Spacing":"1041","Interval_length":"196"},{"Chromosome":"19","Gene_symbol":"PRKCG","Gene_Name":"Protein Kinase C Gamma","Gene_Function":"It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase.","Spacing":"1167","Interval_length":"101"},{"Chromosome":"19","Gene_symbol":"STXBP2","Gene_Name":"Syntaxin Binding Protein 2","Gene_Function":"Involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells.","Spacing":"1302","Interval_length":"110"},{"Chromosome":"19","Gene_symbol":"SYMPK","Gene_Name":"Symplekin","Gene_Function":"Functions in the regulation of polyadenylation and promotes gene expression. ","Spacing":"1427","Interval_length":"100"},{"Chromosome":"19","Gene_symbol":"XRCC1","Gene_Name":"X-Ray Repair Cross Complementing 1","Gene_Function":"Interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway.","Spacing":"1552","Interval_length":"100"},{"Chromosome":"20","Gene_symbol":"C20orf24","Gene_Name":"Chromosome 20 Open Reading Frame 24","Gene_Function":"The function of this gene has not yet been determined.","Spacing":"102","Interval_length":"102"},{"Chromosome":"20","Gene_symbol":"CDH4","Gene_Name":"Cadherin 4","Gene_Function":"Thought to play an important role during brain segmentation and neuronal outgrowth.","Spacing":"302","Interval_length":"175"},{"Chromosome":"20","Gene_symbol":"COMMD7","Gene_Name":"COMM Domain Containing 7","Gene_Function":"Associates with the NF-kappa-B complex and suppresses its transcriptional activity","Spacing":"432","Interval_length":"105"},{"Chromosome":"20","Gene_symbol":"DOK5","Gene_Name":"Docking Protein 5","Gene_Function":"Interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway.","Spacing":"605","Interval_length":"148"},{"Chromosome":"20","Gene_symbol":"HAR1A","Gene_Name":"Highly Accelerated Region 1A ","Gene_Function":"Active in the developing human brain between the 7th and 18th gestational weeks.","Spacing":"755","Interval_length":"125"},{"Chromosome":"20","Gene_symbol":"HAR1B","Gene_Name":"Highly Accelerated Region 1B ","Gene_Function":"No phenotype has yet been reported to our knowledge: this gene's in vivo function is yet unknown. ","Spacing":"905","Interval_length":"125"},{"Chromosome":"20","Gene_symbol":"TMX4","Gene_Name":"Thioredoxin Related Transmembrane Protein 4","Gene_Function":"Catalyze protein folding and thiol-disulfide interchange reactions.","Spacing":"1050","Interval_length":"120"},{"Chromosome":"21","Gene_symbol":"BAGE","Gene_Name":"B Melanoma Antigen","Gene_Function":"Unknown. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.","Spacing":"213","Interval_length":"213"},{"Chromosome":"21","Gene_symbol":"BAGE2","Gene_Name":"B Melanoma Antigen Family Member 2","Gene_Function":"Unknown. Candidate gene encoding tumor antigens.","Spacing":"451","Interval_length":"213"},{"Chromosome":"21","Gene_symbol":"BAGE3","Gene_Name":"B Melanoma Antigen Family Member 3","Gene_Function":"Unknown. Candidate gene encoding tumor antigens.","Spacing":"689","Interval_length":"213"},{"Chromosome":"21","Gene_symbol":"BAGE4","Gene_Name":"B Melanoma Antigen Family Member 4","Gene_Function":"Unknown. 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