Practice Scatter

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<!DOCTYPE html>
<meta charset="utf-8">
<style>

svg {
        font: 10px sans-serif;
        padding: 10px;
    }

.axis,
    .frame {
        shape-rendering: crispEdges;
    }

.axis line {
        stroke: #ddd;
    }

.axis path {
        display: none;
    }

.cell text {
        font-weight: bold;
        text-transform: capitalize;
    }

.frame {
        fill: none;
        stroke: #aaa;
    }

circle {
        fill-opacity: .7;
    }

circle.hidden {
        fill: #ccc !important;
    }

.extent {
        fill: #000;
        fill-opacity: .125;
        stroke: #fff;
    }

div.tooltip {
        position: absolute;
        text-align: center;
        width: 100px;
        height: 150;
        padding: 2px;
        font: 12px sans-serif;
        background: lightgrey;
        border: 0px;
        border-radius: 8px;
        pointer-events: none;
    }

</style>
<body>
<script src="https://d3js.org/d3.v4.min.js"></script>
<script src="https://cdnjs.cloudflare.com/ajax/libs/underscore.js/1.8.3/underscore-min.js"></script>
<script>
    d3.helper = {};

d3.helper.tooltip = function () {
        var tooltipDiv;
        var bodyNode = d3.select('body').node();

function tooltip(selection) {
            selection.on('mouseover.tooltip', function (point) {
                // Clean up lost tooltips
                d3.select('body').selectAll('div.tooltip').remove();
                // Append tooltip
                tooltipDiv = d3.select('body')
                    .append('div')
                    .attr('class', 'tooltip');
                var absoluteMousePos = d3.mouse(bodyNode);
                tooltipDiv
                    .style('left', (absoluteMousePos[0] + 10) + 'px')
                    .style('top', (absoluteMousePos[1] - 30) + 'px');

}

tooltip.attr = function (_x) {
            if (!arguments.length) return attrs;
            attrs = _x;
            return this;
        };

tooltip.style = function (_x) {
            if (!arguments.length) return styles;
            styles = _x;
            return this;
        };

return tooltip;
    };

var width = 600,
        size = 200,
        padding = 30;

var x = d3.scaleLinear().rangeRound([padding / 2, size - padding / 2]);
    var y = d3.scaleLinear().rangeRound([size - padding / 2, padding / 2]);

var color = d3.scaleOrdinal(d3.schemeCategory10);

d3.csv("Patients.csv", function (data) {
        data = _.chain(data).map(function (data) {
            var obj = {};
            _.each(d3.keys(data).filter(function(d) { return d!="TotalDischarges"}), function (key) {
                obj[key] = data[key];
            });

return obj;
        }).value();

// transfer value from string to number
        _.each(data, function (ele) {
            _.each(Object.keys(ele), function (key) {
                if (key != 'State') {
                    ele[key] = +ele[key];
                }
            });
        });

var attr2Domain = {},
            attrs = _.filter(d3.keys(data[0]), function (key) {
                return key !== "State";
            }),
            n = attrs.length;

_.each(attrs, function (attr) {
            attr2Domain[attr] = d3.extent(data, function (ele) {
                return ele[attr];
            });
        });

xAxis.tickSize(size * n);
        yAxis.tickSize(-size * n);

var brush = d3.brush(x, y)
            .extent([[padding / 2, padding / 2], [size - padding / 2, size - padding / 2]]) // brush will out beyond this extent
            .on("start", brushStart)
            .on("brush", brushMove)
            .on("end", brushEnd);

var svg = d3.select("body")
            .append("svg")
            .attr("width", size * n + padding)
            .attr("height", size * n + padding)
            .append("g")
            .attr("transform", "translate(" + padding + "," + padding / 2 + ")");

svg.selectAll(".x.axis")
            .data(attrs)
            .enter().append("g")
            .attr("class", "x axis")
            .attr("transform", function (d, i) {
                return "translate(" + (n - i - 1) * size*0.9 + ",0)";
            })
            .each(function (d) {
                x.domain(attr2Domain[d]);
                d3.select(this).call(xAxis);
            });

svg.selectAll(".y.axis")
            .data(attrs)
            .enter().append("g")
            .attr("class", "y axis")
            .attr("transform", function (d, i) {
                return "translate(0," + i * size*0.9 +")";
            })
            .each(function (d) {
                y.domain(attr2Domain[d]);
                d3.select(this).call(yAxis);
            });
      
      svg.append("text")
        .attr("id", "title")
        .attr("transform", "translate(125, 1)")
      	.style("font-size", 14)
        .text("Discharge Payments per State in the U.S. for 2011");

var cell = svg.selectAll(".cell")
            .data(cross(attrs, attrs))
            .enter()
            .append("g")
            .attr("class", "cell")
            .attr("transform", function (d) {
                return "translate(" + (n - d.i - 1) * size *0.9 + "," + d.j * size*0.9 + ")";
            });

// Titles for the diagonal.
        cell.filter(function (d) {
            return d.i === d.j;
        })
            .append("text")
            .attr("x", padding*.9)
            .attr("y", padding*.9)
            .attr("dy", ".71em")
            .style("fill", "black")
            .text(function (d) {
                return d.x;
            });

cell.call(brush);
        cell.each(plot);

// plot each cell
        function plot(p) {
            var cell = d3.select(this);

x.domain(attr2Domain[p.x]);
            y.domain(attr2Domain[p.y]);

cell.append("rect")
                .attr("class", "frame")
                .attr("x", padding / 2)
                .attr("y", padding / 2)
                .attr("width", size - padding)
                .style("pointer-events", "none")
                .attr("height", size - padding);

circles.on('mousedown', function () {
            });
        }
      
      var brushCell;
        var legendRectSize = 10;
        var legendSpacing = 10;
        var legend = svg.append("g")
            .selectAll("g")
            .data(color.domain())
            .enter()
            .append('g')
            .attr('class', 'legend')
            .attr('transform', function (d, i) {
                var height = legendRectSize;
                var x = n * size;
                var y = (i * height) + 25;
                return 'translate(' + x + ',' + y + ')';
            });
        legend.append('rect')
            .attr('width', legendRectSize)
            .attr('height', legendRectSize)
            .style('fill', color)
            .style('stroke', color)
        		.on("mouseover", function(d) {      
              svg.selectAll("circle").classed("hidden", true);
						});

legend.append('text')
            .attr('x', -legendRectSize+7)
            .attr('y', legendSpacing-3)
        		.style("font-size", 7)
            .style("text-anchor", "end")
            .text(function (d) {
                return d;
            })
        		.on("mouseover", function(d) {
          		svg.selectAll("circle").style("opacity", 0)
              svg.selectAll("circle").filter(function(c) {return c.State == d}).style("opacity", 1);
						})
        		.on("mouseout", function(d) {
          		svg.selectAll("circle").style("opacity", 1);
        });

// Clear the previously-active brush, if any.
        function brushStart(p) {
            if (brushCell !== this) {
                d3.select(brushCell).call(brush.move, null); // clear the brush
                x.domain(attr2Domain[p.x]);
                y.domain(attr2Domain[p.y]);
                brushCell = this;
            }
        }

// Highlight the selected circles.
        function brushMove(p) {
            var s = d3.event.selection;
            if (s) {
                // translate selection area
                var e = [_.map(s[0], x.invert)[0], _.map(s[1], x.invert)[0], _.map(s[1], y.invert)[1], _.map(s[0], y.invert)[1]];
                // hide circles outside of selection
                svg.selectAll("circle").classed("hidden", function (d) {
                    return e[0] > d[p.x] || d[p.x] > e[1]
                        || e[2] > d[p.y] || d[p.y] > e[3];
                });
            }
        }

// If the brush is empty, highlight all circles.
        function brushEnd() {
            if (!d3.event.selection) svg.selectAll(".hidden").classed("hidden", false);
        }
    });

</script>

https://d3js.org/d3.v4.min.js

https://cdnjs.cloudflare.com/ajax/libs/underscore.js/1.8.3/underscore-min.js