grid > horizontal // vertical

<!DOCTYPE html>
<meta charset="utf-8">
<style>
rect {
  stroke: black;
  stroke-width: 1;
  fill: none;
  fill-opacity: .8;
}
</style>
<body>
<script src="https://d3js.org/d3.v4.js"></script>
<script src="https://romsson.github.io/d3-gridding/build/d3-gridding-v0.0.5.js"></script>
<script>
var width = 800,
    height = 800,
    paddingGroups = 5;

var gridding = d3.gridding()
  .size([width, height]);

var svgSquares = d3.select("body").append("svg")
    .attr("width", width)
    .attr("height", height)
  .append("g");

var color = d3.scaleLinear()
    .domain([0, 10])
    .range(["black", "white"]);

var n = 512,
    data = generateData(n);

// Generate data with unique index globally
function generateData(n, offset) {
  offset = offset || 0;
  return d3.range(n).map(function(d, i) {
    return {x: d, y: i, index: i + offset};
  });
}

// Given an SVG element and gridding data
// renders with a depth attribute and key
function render(el, griddingData, depth) {

var squares = el.selectAll(".square.depth_" + depth)
    .data(griddingData, function(d) { return d.index; });

squares.enter().append("rect")
    .attr("class", "square depth_" + depth)
    .attr("width", function(d) { return d.width; })
    .attr("height", function(d) { return d.height; })
    .attr("transform", function(d) { return "translate(" + d.x + "," + d.y + ")"; });

// Prevents to remove unit elements (aka depth 0 elements)
  if(depth > 0) {
    squares.exit().remove();
  }

squares
    .attr("width", function(d) { return d.width; })
    .attr("height", function(d) { return d.height; })
    .attr("transform", function(d) { return "translate(" + d.x + "," + d.y + ")"; });

}

function update(mode, groupBy) {

// Re-orgainize unit-data
  var nested_data = d3.nest()
      .key(groupBy)
      .entries(data);

// Creates group data
  var nbGroups = nested_data.length;

var griddingDataGroups = gridding
          .mode(mode)
          .padding(paddingGroups)
          (nested_data);

render(svgSquares, griddingDataGroups, 1);

// For each group, re-organize the unit elements
  griddingDataGroups.map(function(d, i) {

var cols = gridding.cols();
    var rows = Math.ceil(nbGroups / cols);
    var row =  Math.floor(i / cols);

var grid = d3.gridding()
      .size([d.width, d.height])
      .offset([d.x, d.y])
      .mode((((i + row)  % 2) === 0) ? "horizontal": "vertical")
      .padding(0);

render(svgSquares, grid(nested_data[i].values), 0);
  });

}

var iteration = 0, iterator = 1;

function repeat() {

update("grid", function(e) {
    return e.index % Math.floor(n / Math.pow(2, iteration));
  });

iteration = iteration + iterator;

if(iteration === 9) {
    iterator = -1;
  } else if(iteration === 0) {
    iterator = 1;
  }

setTimeout(repeat, 500);

}

repeat();

</script>

https://d3js.org/d3.v4.js

https://romsson.github.io/d3-gridding/build/d3-gridding-v0.0.5.js